1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, phenylmethyl ester - Names and Identifiers
Name | 1-Cbz-3-piperidinecarboxamide
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Synonyms | 1-N-CBZ-NIPECOTAMIDE 1-Cbz-3-piperidinecarboxamide 1-Cbz-3-(aminocarbonyl)piperidine Benzyl 3-carbaMoylpiperidine-1-carboxylate benzyl 3-carbamoylpiperidine-1-carboxylate 3-Carbamoylpiperidine-1-carboxylic acid benzyl ester 1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, phenylmethyl este 1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, phenylmethyl ester
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CAS | 569348-14-7
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InChI | InChI=1/C14H18N2O3/c15-13(17)12-7-4-8-16(9-12)14(18)19-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2,(H2,15,17) |
1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, phenylmethyl ester - Physico-chemical Properties
Molecular Formula | C14H18N2O3
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Molar Mass | 262.3 |
Density | 1.224g/cm3 |
Boling Point | 475.5°C at 760 mmHg |
Flash Point | 241.4°C |
Vapor Presure | 3.3E-09mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.568 |
1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, phenylmethyl ester - Introduction
The chemical name is an organic compound.
Nature:
It is a solid powder with a white or off-white appearance. Its molecular formula is C14H18N2O2 and its molecular weight is 254.31g/mol. Its melting point is about 85-87°C, and it can be stored and used as a solid at room temperature. It is soluble in organic solvents.
Use:
It has a wide range of applications in organic chemistry. It is often used as an intermediate in the synthesis of complex organic compounds and can be involved in the synthesis of compounds with pharmacological activity. Due to the presence of its piperidine ring and formamide functional group, it has good reactivity, which makes it have great application potential in organic synthesis.
Preparation Method:
The phosphonates can be prepared by reacting 1-Cbz-piperidine with formamide. Specific synthetic methods include catalytic aminolysis with ferrous chloride and formamide combination.
Safety Information:
It is generally relatively safe under normal use conditions. However, it may be irritating to the skin, eyes and mucous membranes. It is recommended to wear appropriate personal protective equipment such as lab gloves and goggles during handling and use. During storage and transportation, contact with oxidizing agents and acids should be avoided to prevent dangerous reactions. In the event of an accident or discomfort, you should seek medical attention and bring details of the compound.
Last Update:2024-04-10 22:29:15